Monoclonal antibodies (mAbs) have the potential to create new ways of preventing and treating serious infections to improve individual outcomes and address the threat of antibiotic resistance. Selectively and safely targeting pathogens through their pathogenic processes has the potential to provide a new way of treating or even preventing infection for those at high-risk.

Our current monoclonal antibody programs address specific bacterial and viral pathogens. Our Phase 2 program, ASN100, selectively targets Staphylococcus aureus virulence rather than directly killing the bacteria, potentially allowing Arsanis to combat critical infections without contributing to antibiotic resistance or damaging the patient’s microbiome.